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General information: Gestanin is designed to be taken during pregnancy. Gestanin is progestogen that is similar to the hormone progesterone. It is used to prevent habitual spontaneous abortion and premature labor. Women that suffer from progesterone deficiency, progestogen is proven to help in carrying fetuses to the term. It works by stimulating the secretory phase of endometrium cyclic changes which results in creation of appropriate conditions for the development of fertilized egg. It reduces contractive activity and sensitivity to oxytocin of the myometrium. It also stimulates the growth of lactiferous glands’ acini, increases fat deposits, facilitates liver glycogen storage, increases glucose utilization and improves production of aldosterone by the adrenal glands.
Storage: This medication should be stored at room temperature between 20-25 C (68-77 F) away from sources of light, heat and moisture. Avoid storing it in the bathroom. Keep all drugs away from reach of children and pets.
Missed dose: If you have missed your dose, take it as soon as possible. In case it is near the time for the next dose, avoid taking the missed dose and keep your ordinary dosing schedule. Avoid compensating a missed dose by taking an extra one. It is also desirable to consult your doctor about follow-up actions if you have missed a few doses.
Possible side effect: A range of side effects known to be associated with this medicine includes: sickness, vomiting, giddiness, swelling, skin reactions such as rash and itching, breast tenderness, menstrual spotting between periods, dyspepsia, diarrhea, thrombophlebitis, thromboembolism, acne, weight gain, jaundice, hyperthermia, insomnia, mood changes, confusion, depression. In case these symptoms are bothersome, immediately inform your doctor.
Contraindications: This medicine is contraindicated in patients suffering from thrombophlebitis, cerebral blood circulation disorders, genital tumors, toxaemia (toxins in the bloodstream), and herpes. Due to occurrences of hypersensitivity to this medicine, Dubin-Johnson syndrome (an increase of conjugated bilirubin without elevation of liver enzymes) or Rotor syndrome (a benign autosomal recessive bilirubin disorder) this medication cannot be taken. It can also excrete into milk, so breastfeeding women should not take this medicine as well.
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